Xiaflex is a prescription medication used to treat adult men with Peyronie’s Disease who have a “plaque” that can be felt and a curve in their penis greater than 30 degrees when treatment is started.

What is Peyronie’s Disease?

Peyronie’s Disease is a condition where scar tissue develops in the penis, forming a plaque under the skin. The plaque often builds up so much that it can cause a bend in the penis, or an obvious indent during an erection. Typically, those affected can feel the plaque buildup through the skin, and many experience pain.

Scar tissue buildup is likely caused by minor injury, such as hitting the partner’s pelvic bone during sex, sports or accidents, as well as fibrosis.

The majority of patients with Peyronie’s Disease notice the plaque on the top of the penis, causing an upward curvature. If the scar tissue forms on the bottom of the penis, it turns downward or sideways. In some situations, the scar tissue forms completely around the penis, causing the penis to appear to shorten. In this situation, the scar tissue feels almost bone-like.

Peyronie’s Disease is common and treatable, though 3 out of 4 men feel stressed and depressed. Talk with your Jackson Urologist about options — Xiaflex could be perfect for you. This treatment is also used to treat some cases of erectile dysfunction.

What is Xiaflex?

Xiaflex is an injection composed of collagenase, an enzyme that breaks down the collagen and scar tissue buildup in the penis.

Your Jackson Urologist will inject the medication into the penis where there is the most scar tissue. The penis will be wrapped or bandaged to prevent the medicine from leaking out. In one to three days, the urologist will offer another injection. After the second injection, your doctor will perform a straightening procedure. They will also give you directions as far as stretching and straightening the penis in a form of therapy.

Do not have sex during the treatment time period, or until your doctor gives you the all clear.

After treatment

You may notice some swelling, bruising or itching at the injection site. This is normal. Contact your Urologist with any concerns you may have including excessive swelling or bleeding.

After six weeks — if the scar tissue returns or you and your doctor feel more treatment is needed — the procedure may be repeated. Treatment can repeat up to four times.